Publications
- 2008
- Fernandes R, Bentley WE. (2008).
AI-2 biosynthesis module in a magnetic nanofactory alters bacterial response via localized synthesis and delivery.
Biotechnol Bioeng. 2008 Aug 8. [Epub ahead of print]
- Nde CW, Jang HJ, Toghrol F, Bentley WE. (2008).
Toxicogenomic response of Pseudomonas aeruginosa to ortho-phenylphenol.
BMC Genomics. 2008 Oct 10;9(1):473. [Epub ahead of print]
- Jang HJ, Nde C, Toghrol F, Bentley WE. (2008).
Microarray analysis of toxicogenomic effects of ortho-phenylphenol in Staphylococcus aureus.
BMC Genomics. 2008 Sep 15;9:411.
- Hebert CG, Valdes JJ, Bentley WE. (2008).
Beyond silencing-engineering applications of RNA interference and antisense technology for altering cellular phenotype.
Curr Opin Biotechnol. 2008 Sep 25. [Epub ahead of print]
- Fernandes R, Bentley WE. (2008).
AI-2 biosynthesis module in a magnetic nanofactory alters bacterial response via localized synthesis and delivery.
Biotechnol Bioeng. 2008 Aug 8. [Epub ahead of print]
- Shi XW, Liu Y, Lewandowski AT, Wu LQ, Wu HC, Ghodssi R, Rubloff GW, Bentley WE, Payne GF.
Chitosan. (2008). biotinylation and electrodeposition for selective protein assembly.
Macromol Biosci. 2008 May 13;8(5):451-7.
- Shi XW, Wu HC, Liu Y, Tsao CY, Wang K, Kobatake E, Bentley WE, Payne GF.
(2008). Chitosan fibers: versatile platform for nickel-mediated protein assembly.
Biomacromolecules. 2008 May;9(5):1417-23. Epub 2008 Apr 10.
- Jang HJ, Chang MW, Toghrol F, Bentley WE.
(2008). Microarray analysis of toxicogenomic effects of triclosan on Staphylococcus aureus.
Appl Microbiol Biotechnol. 2008 Mar;78(4):695-707. Epub 2008 Jan 22.
- Luo X, Lewandowski AT, Yi H, Payne GF, Ghodssi R, Bentley WE, Rubloff GW.
(2008). Programmable assembly of a metabolic pathway enzyme in a pre-packaged reusable bioMEMS device.
Lab Chip. 2008 Mar;8(3):420-30. Epub 2008 Jan 14.
- Lewandowski AT, Yi H, Luo X, Payne GF, Ghodssi R, Rubloff GW, Bentley WE.
(2008). Protein assembly onto patterned microfabricated devices through enzymatic activation of fusion pro-tag.
Biotechnol Bioeng. 2008 Feb 15;99(3):499-507.
- 2007
- Chang MW, Toghrol F, Bentley WE. (2007). Toxicogenomic response to chlorination includes induction of major virulence genes in Staphylococcus aureus. Environ Sci Technol. 2007 Nov 1;41(21):7570-5.
- Lee, J., Bansal, T., Jayaraman, A., Bentley, W.E., and T.K. Wood (2007). Enterohemorrhagic Escherichia coli Biofilms are Inhibited by 7-Hydroxyindole and Stimulated by Isatin, Applied and Environmental Microbiology. Abstract
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Yung, C.W., Tullman, J.A., Payne, G.F., Bentley, W.E., and T.A. Barbari (2007). Transglutaminase Crosslinked Gelatin as a Tissue Engineering Scaffold, Journal of Biomedical Materials Research A. Abstract
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Li, J., Attila, C., Wang, L., Wood, T.K., Valdes, J.J., and W.E. Bentley (2007). Quorum Sensing in E. coli is Signaled by AI-2/LsrR: Effects on sRNA and Biofilm Architecture, Journal of Bacteriology, 73:4100-4109. Abstract
- Fernandes, R., Tsao, C.Y., Hashimoto, Y., Wang, L., Wood, T.K., Payne, G.F., and W.E. Bentley (2007). Magnetic Nanofactories: Localized Synthesis and Delivery of Quorum-Sensing Signaling Molecule Autoinducer-2 to Bacterial Cell Surfaces, Metabolic Engineering, 9:228-239.
Abstract
- Small, D.A., Chang, W., Bentley, W.E., and F. Toghrol (2007). Toxicogenomic Analysis of Sodium Hypochlorite Antimicrobial Mechanisms in Pseudomonas aeruginosa, Applied Microbiology and Biotechnology, 74:176-185.
Abstract
- Kim, E.J., Kramer, S.F., Hebert, C.G., Valdes, J.J., and W.E. Bentley (2007). Metabolic Engineering of the Baculovirus-Expression System via Inverse “Shotgun” Genomic Analysis & RNA Interference (dsRNA) Increases Product Yield and Cell Longevity, Biotechnology and Bioengineering, 98:645-654. Abstract
- March, J.C., and W.E. Bentley (2007). RNAi-based Tuning of Cell Cycling in Drosophila S2 cells- effects on Recombinant Protein Yield, Applied Microbiology and Biotechnology, 73: 1128-1135. Abstract
- Koev, S.T., Powers, M. A. Powers, Yi, H.M., Wu, L-Q., Bentley, W.E., Rubloff, G.W., Payne, G.F., and R. Ghodssi, (2007). Mechano-transduction of DNA Hybridization and Dopamine Oxidation through Electrodeposited Chitosan Network, Lab on a Chip, 7:103-111.
Abstract
- Small, D.A, Chang, W., Toghrol, F., and W.E. Bentley (2007). Comparative Global Transcription Analysis of Sodium Hypochlorite, Peracetic Acid, and Hydrogen Peroxide on Pseudomonas aeruginosa, Applied Microbiology and Biotechnology, 76:1093-1105. Abstract
- O’Connell, K.P., Kovaleva, E., Campbell, J.H., Anderson, P.E., Brown, S.G., Davis, D.C., Valdes, J.J., Welch, R.W., Bentley, W.E. and N.A. van Beek (2007). Production of a Recombinant Antibody Fragment in Whole Insect Larvae, Molecular Biotechnology, 36:44-51. Abstract
- Hung, C-W., Holoman, T.R.P., Kofinas, P., and W.E. Bentley (2007). Towards Oriented Assembly of Proteins onto Magnetic Nanoparticles, Biochemical Engineering Journal.
- Saini, S.S., Stanford, C., Lee, S.M., Park, J., DeShong, P., Bentley, W.E., and Dagenais, M. (2007). Monolayer Detection of Biochemical Agents Using Etched-Core Fiber Bragg Grating Sensors, IEEE Photonics Technology Letters, 19:1341-1343. Abtract
- Lewandowski, A.T., Yi, H., Luo, X., Payne, G.F., Ghodssi, R., Rubloff, G.W., and W.E. Bentley (2007). Protein Assembly onto Patterned Microfabricated Devices through Enzymatic Activation of Fusion Pro-tag. Biotechnology and Bioengineering. Abstract
- March, J.C., and W.E. Bentley (2007). Methods for gene silencing with RNAi, Methods in Molecular Biology, 388:424-434. Abstract
- Hu, Y.C., and W.E. Bentley (2007). Alternative Bioreactor Strategy for Probing Infection and Production, Methods in Molecular Biology, 388:419-426. Abstract
- Cha, H.J., and W.E. Bentley (2007). Monitoring and Visualization of Baculovirus Infection Using Green Fluorescent Protein Strategy, Methods in Molecular Biology, 388:407-418. Abstract
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2006
- Lewandowski, A.T., Small, D.A., Chen, T., Payne, G.F., and
W.E. Bentley (2006) Tyrosine-based “activatable pro-tag”:
enzyme-catalyzed protein capture and release, Biotechnology and
Bioengineering, 93:1207-1215.
- Chang, W., Small, D.A., Toghrol, F., and W.E. Bentley (2006)
Global Transcriptome Analysis of Staphylococcus aureus Response
to Hydrogen Peroxide, Journal of Bacteriology, 188:1648-1659.
- Gonzalez Barrios, A.F., Zuo R., Hashimoto, Y., Yang, L., Bentley
W.E., and T.K. Wood (2006) Autoinducer 2 Controls Biofilm Formation
in Escherichia coli Through a Novel Motility Quorum-sensing Regulator
(MqsR, B3022), Journal of Bacteriology, 188:205-316.
- Bleckwenn, N. A. and Bentley, W. E. (2006) Systems and Technology
Involving Bacteria, In CRC BME Handbook: Tissue Engineering and
Artificial Organs (JD Bronzino, ed.) CRC Press, Boca Raton, FL,
2.1-2.10.
- Yung, C., Barbari, T.A., and W.E. Bentley (2006) Integrated
Non-Invasive System for Quantifying Secreted Human Therapeutic
hIL2, Biotechnology and Bioengineering.
- Yang, L., Portugal, F.H., and W.E. Bentley (2006) Conditioned
Medium from Listeria innocua Stimulate Emergence from a Resting
State not in Response to Quorum Sensing Autoinducer AI-2, Biotechnology
Progress, 22:387-393.
- March, J.C., and W.E. Bentley (2006) Engineering Eukaryotic
Signal Transduction with RNAi: Enhancing Drosophila S2 Cell Growth
and Recombinant Protein Synthesis via Silencing of TSC1. Biotechnology
and Bioengineering.
- Park, J.J., Valentine, T.M., Yi, H., Payne, G.F., Bentley,
W.E., Ghodssi, R., and Gary W. Rubloff (2006) In situ Biomolecule
Assembly in Completely Packaged Microfluidic Devices, Lab on a
Chip.
- Yung, C.W., Barbari, T.A., and W.E. Bentley (2006) Counteracting
Apoptosis and Necrosis with Hypoxia Responsive Expression of Bcl-2D,
Metabolic Engineering.
- Cresce, A.V., Silverstein, J.S., Bentley, W.E., and P. Kofinas
(2006) Nanopatterning of Recombinant Proteins using Block Copolymer
Templates, Macromolecules, 39, 5826-5829.
- Dalal, N.G., Cha, H.J., Kramer, S.F., Kostov, Y., Rao, G. and
W.E. Bentley (2006) Rapid Non-invasive Monitoring of Baculovirus
Infection for Insect Larvae Using Green Fluorescent Protein Reporter
Under Early-to-Late Promoter and a GFP-Specific Optical Probe,
Process Biochemistry, 41:947-950.
- Li, J., Wang, L., Hashimoto, Y., Tsao, C-Y., Wood, T.K., Valdes,
J.J., Zafiriou, E., and W.E. Bentley (2006) Stochastic Model of
E. coli AI-2 Quorum Signal Circuit Reveals Alternative Synthesis
Pathways, Nature Molecular Systems Biology.
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2005
- Wang, L., Hashimoto, Y., Tsao, C.-Y., Valdes, J.J., and W.E.
Bentley (2005) cAMP and cAMP Receptor Protein (CRP) Influence
Both Synthesis and Uptake of Extracellular Autoinducer-2 in Escherichia
coli, Journal of Bacteriology, 187:2066-76.
- Yi, H., Wu, L.Q., Rubloff, G.W., Ghodssi, R., Payne, G.F.,
and Bentley, W.E., (2005) Signal-Directed Sequential Assembly
of Biomolecules on Patterned Surfaces. Langmuir, 2:2104-2107.
- Tao, Y., Bentley, W.E., and T.K. Wood, (2005) Regiospecific
Oxidation of Naphthalene and Fluorene by Toluene Monooxygenase
and Engineered Toluene 4-Monooxygenase of Pseudomonas mendocina
KR1, Biotechnology and Bioengineering, 90:85-94.
- Cha, H.J., Shin, H.S., Lim, H.J., Cho, H.S., Dalal, N.N., Pham,
M.Q., and W.E. Bentley (2005) Comparative Production of Human
Interleukin-2 Fused with Green Fluorescent Protein in Several
Recombinant Expression Systems, Biochemical Engineering Journal,
24:225-233.
- Lu CH, Albano CR, Bentley WE, and G. Rao (2005) Quantitative
and kinetic study of oxidative stress Regulons using green fluorescent
protein, Biotechnology and Bioengineering, 89: 574-587.
- Bleckwenn, N. A., Bentley, W. E., Shiloach, J., (2005) Vaccinia
Virus-Based Expression of gp120 and EGFP: Survey of Mammalian
Host Cell Lines, Biotechnology Progress, 21:186-191.
- Bleckwenn, N. A., Bentley, W. E., Shiloach, J., (2005) Evaluation
of Production Parameters with the Vaccinia Virus Expression System
Using Microcarrier Attached HeLa Cells, Biotechnology Progress,
21:554-561.
- Bleckwenn, N. A., Bentley, W. E., Shiloach, J., (2005) Production
of Recombinant Protein Using the HeLa S3-Vaccinia Virus Expression
System: Bioreactor Perfusion and Effects of Post-Infection Temperature,
Journal of Bioscience, Biotechnology and Biochemistry, 69:1065-1072.
- Bleckwenn, N. A., Golding, H., Bentley, W. E., Shiloach, J.,
(2005) Production of Recombinant Proteins by Vaccinia Virus in
a Microcarrier Based Mammalian Cell Perfusion Bioreactor, Biotechnology
and Bioengineering, 90:663-674.
- Tao, Y, Bentley, W.E., and T.K. Wood (2005) Phenol and 2-Naphthol
Production by Toluene 4-Monooxygenases Using an Aqueous/Dioctyl
Phthalate system, Applied Microbiology & Biotechnology, 68:614-621.
- Dalal, N.G., Bentley, W.E., and H.J. Cha (2005) Facile Monitoring
of Baculovirus Infection for Foreign Protein Expression under
Very Late Polyhedrin Promoter using Green Fluorescent Protein
Reporter under Early-to-Lte Promoter, Biochemical Engineering
Journal, 24:27-30.
- Cha, H.J., Dalal, N.G., and W.E. Bentley (2005) Secretion of
Human Interleukin-2 Fused with Green Fluorescent Protein in Recombinant
Pichia pastoris, Applied Biochemistry and Biotechnology, 126:1-11.
- Powers, M.A., S. T. Koev, A. Schleunitz, H. Yi, V. Hodzic,
W. E. Bentley, G. F. Payne, G. W. Rubloff, and R. Ghodssi (2005)
Integrated Optical Sensing of Biofunctionalized Sites in BioMEMS,
Lab on a Chip, 5:583-586.
- Chryssis, A.N., Saini, S.S., Lee, S.M., Yi, H.M., Bentley,
W.E., and M. Dagenais (2005) Detecting Hybridization of DNA by
Highly Selective Evanescent Field Etched Core Fiber Bragg Grating
Sensors, IEEE Journal of Selected Topics in Quantum Electronics,
11:864-872.
- Chang, W., Small, D.A. Toghrol, F., and W.E. Bentley (2005)
Microarray Analysis of Toxicogenomic Effects of Peracetic Acid
on Pseudomonas aeruginosa, Environmental Science & Technology,
39:5893-5899.
- Chang, W., Small, D.A., Toghrol, F., and W.E. Bentley (2005)
Microarray Analysis of Pseudomonas aeruginosa Reveals Induction
of Pyocin Genes in Response to Hydrogen Peroxide, BMC Genomics,
6.115-129.
- Yi, H., Nisar, S., Lee, SY, Powers, MA, Bentley, WE., Payne,
GF, Ghodssi, R., Rubloff, GW, Harris, MT, Culver, JN (2005) Patterned
Assembly of Genetically Modified Viral Nanotemplates via Nucleic
Acid Hybridization, Nano Letters, 5:1031-1936.
- Wang, L., Li, J., March, J.C., Valdes, J.J., and W.E. Bentley
(2005), luxS-Dependent Gene Regulation in Escherichia coli K-12
Revealed by Genomic Expression Profiling, Journal of Bacteriology,
187:8350-8360.
- Yi, H., Wu, L.Q., Bentley, W.E., Ghodssi, R., Rubloff, G.W.,
Culver, J.N., Payne, G.F., (2005) Biofabrication with Chitosan,
Biomacromolecules, 6:2881-2894.
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2004
- March, J.C. and W.E. Bentley (2004) Insulin stimulates dsRNA
uptake in Drosophila S2 cells, BioTechniques, 37:898-890.
- Mohaddes-Ardabili, L., Martinez-Miranda, L.J., Salamanca-Riba,LG.,
Christou, A., Silverman, J., Bentley, W.E., and M. Al-Sheikhly(2004)
Preferred Orientation of DNA Oligonucleotide Probes on the (2x4)Reconstructed
Surface of (001) GaAs, Journal of Applied Physics, 95:6021-6024.
- Lu, C., Bentley, W.E., and G. Rao(2004) A High Throughput Approach
to Promoter Study Using Green Fluorescent Protein, Biotechnology
Progress, 20:1634-1640.
- Tao Y, Fishman A, Bentley WE, and T.K. Wood (2004) Altering
toluene 4-monooxygenase by active-site engineering for the synthesis
of 3-methoxycatechol, methoxyhydroquinone, and methylhydroquinone,
Journal of Bacteriology, 186:4705-13.
- March, J.C. and W.E. Bentley (2004) Quorum sensing and bacterial
cross-talk in biotechnology, Current Opinion in Biotechnology,
15(5):495-502.
- Fishman A, Tao Y, Bentley WE, and T.K. Wood (2004) Protein
engineering of toluene 4-monooxygenase of Pseudomonas mendocina
KR1 for synthesizing 4-nitrocatechol from nitrobenzene, Biotechnology
& Bioengineering, 87(6):779-90.
- Tao, Y., Fishman, A., Bentley, W.E., and T.K. Wood (2004) Oxidation
of Benzene to Catechol and 1,2,3-Trihydroxybenzene by Toluene
4-Monooxygenase of Pseudomonas mendocina KR1 and Toluene 3-Monooxygenase
of Ralstonia pickettii PKO1, Applied & Environmental Microbiology,
7:3814-3820.
- Cha, H.J., Dalal, N.G., and W.E. Bentley (2004) In vivo Monitoring
of Human Interleukin-2 using Green Fluorescent Protein Fusion
Partner in Pichia Pastoris, Biotechnology letters, 26:1157-1162.
- Yi, H., Wu, L.Q., Ghodssi, R., Rubloff, G.W., Payne, G.F.,
and W.E. Bentley (2004) A Robust Technique for Assembly of Nucleic
Acid Hybridization Chips Based on Electrochemically Templated
Chitosan, Analytical Chemistry, 76:365-372.
- Fernandes,R., Yi, H., Wu, L.Q., Rubloff, G.w., Ghodssi, R.,
Bentley, W.E., and G.F. payne (2004) Thermo-Biolithography: A
Technique for Patterning Nucleic Acids and Proteins, Langmuir,
20:906-913.
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2003
- Chen, T., Small, D.A., Wu, L.Q., McDermot, M.K., Bentley, W.E.,
and G.F. Payne (2003) Enzymatic Methods for in Situ Entrapment
and Cell Release, Biomacromolecules, 4:1558-1563.
- Kastantin MJ, Li S, Gadre AP, Wu LQ, Bentley, WE, Payne GF,
Rubloff GW, Ghodssi R (2003) Integrated fabrication of polymeric
devices for biological applications, Sensors and Materials, 15(6):295-311.
- Chen, T., Yi, H., Rubloff, G.W., Ghodssi, R., Bentley, W.E.,
and G.F. Payne (2003) Nature-inspired Creation of Protein-polysaccharide
Conjugate and its Subsequent Assembly onto a Patterned Surface,
Langmuir, 19:9382-9386.
- Lu, C., Bentley, W.E., and G. Rao (2003) Comparisons of Oxidative
Stress Respponse Genes in Aerobic Escherichia coli Fermentations,
Biotechnology and Bioengineering, 83:864-870.
- Mohaddes-Ardabili, L., Martinez-Miranda, L.J., Silverman, J.,
Christou, A., Salamanca-Riba, L.G., Bentley, W.E., Ohuchi, F.,
and M. Al-Sheikhly (2003) Attachment of DNA probes on gallium
arsenide surface, Applied Physics letters, 83:192-194.
- Fernandes, R., Wu, L.Q., Chen, T., Yi, H., Rubloff, G.W., Ghodssi,
R., Bentley, W.E., and G.F.Payne (2003) Electrochemically-Induced
Deposition of a Polysaccharide Hydrogel onto a Patterned Surface,
Langmuir, 19:4058-4062.
- Kramer, S.F., and W.E. Bentley (2003) RNA Interference as a
Metabolic Engineering Tool: Potential for in vivo Control of Protein
Expression in an Insect Larval Model, Metabolic Engineering, 5:183-190.
- Wu, C.F.,Bentley, W.E., Valdes, J.J., and J.W. Sekowski (2003)
DNA microarray for discrimination between pathogeic O157:H7 EDL933
and non-pathogenic Escherichia coli strains, Biosensors and Bioelectronics,
19:1-8.
- March, J.C., Rao, G., and W.E. Bentley (2003) Biotechnological
Applications of Green Florescent Protein, Applied Microbiology
and Biotechnology, 62:303-315.
- Bleckwenn, N.A., Bentley, W.E., and J. Shiloach (2003) Investigating
Protein Production Strategies with Recombinant Vaccinia virus,
Biotechnology Progress, 19:130-136.
- Hyunmin Yi, H., Wu, L.Q., Sumner, J.J., Gillespie, J.B., Payne,
G.F.,and W.E. Bentley (2003) Chiosan Scaffolds for Biomolecular
Assembly: Coupling Nucleic Acid Probes for Detecting Hybridization,
Biotechnology and Bioengineering, 83:646-652.
- Kramer, S.F., Kostov, Y., Rao, G., and W.E. Bentley (2003)
Ex Vivo Monitoring of Protein Production in Baculovirus-Infected
Trichoplusia ni Larvae with a GFP-Specific Optical Probe, Biotechnology
and Bioengineering, 83:241-247.
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2002
- Lu, C., Albano, C.R., Bentley, W.E., and G. Rao (2002) Differential
Rates of Gene Expression Monitored by Green Fluorescent Protein,
Biotechnology and Bioengineering, 79:429-37.
- DeLisa, M.P., and W. E. Bentley (2002) Bacterial Autoinduction:
Looking Outside the Cell for New Metabolic Engineering Targets,
Microbial Cell Factories, 1:5-12.
- Wu, Li-Qun, Yi, H., Li, S., Rubloff, G.W., Bentley, W.E., Ghodssi,
R.,and G.F. Payne, (2002) Spatially-selective Deposition of a
Reactive Polysaccharide Layer onto a Patterned Template, Langmuir,
19:519-524.
- Wu, Li-Qun, Gadre, A.P, Yi, Hyunmin, Kastantin, M.J., Rubloff,
G.W., Bentley, W.E., Payne, G.F., and Reza Ghodssi, (2002) Voltage-dependent
Assembly of the Polysaccharide Chitosan onto an Electrode Surface,
Langmuir, 8:8620-8625.
- Li, J., Xu, H., Herber, W.K., Bentley, W.E., and G. Rao (2002)
Integrated Bioprocessing in Saccharomyces cerevisiae Using Green
Fluorescent Protein as a Fusion Partner, Biotechnology and Bioengineering,
79:682-693.
- Li, J., Xu, H., Bentley, W.E. and Rao, G. (2002) Impediments
to Secretion of Green Fluorescent Protein and its Fusion from
Saccharomyces cerevisiae, Biotechnology Progress, 18:831-838.
- Wu, C.F., Cha, H.J., Valdes, J.J., and W. E. Bentley (2001)
GFP-Immobilized Enzymes: Degradation of Paraoxon via Organophosphorous
Hydrolase in a Packed Column, Biotechnology and Bioengineering,
77:212-218.
- Cha, H.J., Dalal, N.G., Pham, M.-Q., Kramer, S.F., Vakharia,
V.N., and W.E. Bentley (2002) Monitoring Foreign Protein Expression
from Baculovirus p10 and polh Promoters in Insect Larvae, BioTechniques,
35:986-991 .
-
2001
- Wu, C.F., Valdes, J.J., Rao, G., and W.E. Bentley (2001) Enhancement
of Organophosphorus Hydrolase Yield in E. coli Using Multiple
Gene Fusions, Biotechnology and Bioengineering, 75:100-103.
- Gotoh, T., Miyazaki, Y., Sato, W., Kikuchi, K.-I., and Bentley,
W. E.(2001) Proteolytic Activity and Recombinant Protein Production
of Virus-infected Sf-9 Insect Cell Culture Supplemented with Cysteine
Protease and Carboxyl Protease Inhibitors, Journal of Bioscience
and Bioengineering, 92:248-255 .
- Cho, H.S., Shin, H.S., Bentley, W.E., and H. J. Cha (2001)
Partial Recovery of Cell Membrane Bounded Human Interleukin-2
Fusion Protein from Insect Cell Debris by Using Various Detergent
Extractions, Biotechnology Letters, 23:1957-1961 .
- DeLisa, M.P., Gill, R.T., and W.E. Bentley (2001) Mapping Stresses
in Escherichia coli to Improve Yield, EFB Recombinant Protein
Production, Kluwer Academic Publishers, pp.43-54 .
- Hu, Y.-C., and W. E. Bentley (2001) The Effect of MOI Ratio
on the Composition and Yield of Chimeric Infectious Bursal Disease
Virus-like Particles by Baculovirus Co-infection: Deterministic
Predictions and Experimental Results, Biotechnology and Bioengineering,
75:104-119.
- Srivastava, R., Peterson, M.S., and W.E. Bentley (2001) Stochastic
Kinetic Analysis of the Escherichia coli Stress Circuit Using
s32 Targeted Antisense, Biotechnology and Bioengineering, 75:120-129.
- 78. Wu, C.F., Valdes, J.J. and W.E. Bentley (2001) Effects
of in situ Cobalt Ion Addition on the Activity of a GFP-OPH Fusion
Protein: The Fermentation Kinetics, Biotechnology Progress, 17:606-611.
- DeLisa, M.P., Chae, H.J., Rao, G., Weigand, W.A., Valdes, J.J.,
and W.E. Bentley (2001) Generic Model Control of Induced Protein
Expression in High Cell Density Cultivation of Escherichia coli
Using On-line GFP-Fusion Monitoring. Bioprocess and Biosystems
Engineering, 24:83-91.
- Lee, T.S., Chan, S.H., Weigand, W.A., and W.E. Bentley (2001)
A Metabolic Model for Thiodiglycol Degradation: Capacity Constraint
Leads to Byproduct Accumulation. Bioprocess and Biosystems Engineering,
24:33-38.
- Albano, C. R., Lu, Canghai, Bentley, W.E., and Govind Rao.
(2001) High Throughput Studies of Gene Expression Using Green
Fluorescent Protein-Oxidative Stress Promoter Probe Constructs:
The Potential for Living Chips. J. Biomolecular Screening. 6:421-428.
- DeLisa, M.P., Valdes, J.J., and W.E. Bentley (2001) Quorum
Signaling via AI-2 Communicates the “Metabolic Burden?Associated
with Heterologous Protein Expression in Escherichia coli. Biotechnology
and Bioengineering, 75:439-450.
- DeLisa, M.P., Wu, C.F., Wang, L., Valdes, J.J., and W.E. Bentley
(2001) DNA Microarray-Based Identification of Genes Controlled
by AI-2-stimulated Quorum Sensing in Escherichia coli. Journal
of Bacteriology. 183:5239-5247.
- Gotoh, T., Miyazaki, Y., Kikuchi, KI, and W.E. Bentley (2001)
Investigation of Sequential Behavior of Carboxyl Protease and
Cysteine Protease Activities in Virus-infected Sf-9 Insect Cell
Culture by Inhibition Assay, Applied Microbiology and Biotechnology
,56:742-749.
- Gill, R.T., DeLisa, M.P., Valdes, J.J., and W.E. Bentley (2001)
Genomic Analysis of High Cell Density Recombinant Escherichia
coli Fermentation and “Cell Conditioning?for Improved Recombinant
Protein Yield. Biotechnology and Bioengineering, 72: 85-95.
- DeLisa, M.P., Valdes, J.J., and W.E. Bentley (2001) Mapping
Stress-Induced Changes in Autoinducer AI-2 Production in Chemostat
Cultivated Escherichia coli K-12, Journal of Bacteriology, 183:2918-2928.
- Chen, T., Vazquez-Duhalt, R., Wu, C.F., Bentley, W.E., and
G.F. Payne (2001) Combinatorial Screening for Enzyme-mediated
Coupling. Tyrosinase-Catalyzed Coupling to Create Protein-Chitosan
Conjugates, Biomacromolecules. 2:456-452.
-
2000
- Cha, H.J., Wu, C.-F., Valdes, J.J., Rao, G., and W. E. Bentley
(2000) Observations of Green Fluorescent Protein as a Fusion Partner
in Genetically Engineered Escherichia coli: Monitoring Protein
Expression and Solubility, Biotechnology and Bioengineering, 67:565-574.
- Wu, C.-F., Cha, H.J., Rao, G., Valdes, J.J., and W. E. Bentley
(2000) A Green Fluorescent Protein Fusion Strategy for Monitoring
the Expression, Cellular Localization, and Separation of Biologically
Active Organophosphorous Hydrolase, Applied Microbiology and Biotechnology,
54:78-83.
- Hu, Y.C., and W. E. Bentley (2000) A Kinetic and Statistical
Thermodynamics-based Model for Baculovirus Infection and Virus-like
Particle Assembly, Chemical Engineering Science, 55:3991-4008.
- Chae, H.J., DeLisa, M.P., Cha, H.J., Weigand, W.A., Rao, G.,
and W.E. Bentley (2000) A Framework for On-line Optimization of
Recombinant Protein Expression in High Cell Density Escherichia
coli Cultures using GFP-Fusion Monitoring, Biotechnology and Bioengineering,
69: 275-285.
- Gill, R.T., Valdes, J.J., and W.E. Bentley (2000) A Comparative
Study of Global Stress Gene Regulation in Response to Overexpression
of Recombinant Proteins in Escherichia coli. Metabolic Engineering,
2: 178-189.
- DeLisa, M.P., Zhang, Z., Shiloach, M., Pilevar, S., Davis, C.C.,
Bentley, W.E., and J.S. Sirkis (2000) Evanescent Wave Long Period
Fiber Bragg Grating as an Immobilized Antibody Biosensor. Analytical
Chemistry, 72:2895-2900.
- Gill, R.T., Shiloach, M.S., DeLisa, M.P., Holoman, T.R., and
W.E. Bentley (2000) OmpT Expression and Activity Increase in Response
to Recombinant Protein Chloramphenicol Acetyltransferase Overexpression
and Heat Shock in E. coli. Journal of Microbiology and Molecular
Biotechnology. 2:283-289.
- Lee, T.-S. , Chan, S.H., Weigand, W.A., and W. E. Bentley (2000)
Biocatalytic Transformation of [(2-Hydroxyethyl)thio]acetic Acid
and Thiodiglycolic Acid from Thiodiglycol by Alcaligenes xylosoxydans
ssp. xylosoxydans (SH91), Biotechnology Progress, 16:363-367.
- Srivastava, R., Cha, H.J., Peterson, M.S., and W.E. Bentley
(2000) Antisense Downregulation of s32 as a Transient Metabolic
Controller in Escherichia coli: Effects on Yield of Active Organophosphorous
Hydrolase, Applied and Environmental Microbiology, 66: 4366-4371.
- Madurawe, R., Chase, T., Tsao, E.I., and W.E. Bentley (2000)
A Recombinant Lipoprotein Antigen Against Lyme Disease Expressed
in E. coli: Fermentor Operating Strategies for Improved Yield.
Biotechnology Progress, 16:571-576.
- Li, J., Wang, S., VanDeusen, W.J., Schultz, L.D., George, H.A.,
Herber, W.K., Chae, H.J., Bentley, W.E., Rao, G. (2000) Green
Fluorescent Protein in Saccharomyces cerevisiae: Real-Time Studies
of the GAL1 Promoter, Biotechnology and Bioengineering, 70:187-196.
-
1999
- Pham, M.Q., Naggie, S., Wier, M., Cha, H.J., and W.E. Bentley
(1999) Human Interleukin-2 Production in Insect (Trichoplusia
ni) Larvae: Effects and Partial Control of Proteolysis, Biotechnology
and Bioengineering, 62:175-182.
- Cha, H.J., Srivastava, R., Vakharia, V., Rao, G., and W. E.
Bentley (1999) Green Fluorescent Protein as a Non-invasive "Stress
Probe" in Resting Recombinant Escherichia coli Culture, Applied
and Environmental Microbiology, 65:409-414.
- Cha, H.J., Dalal, N.G., Vakharia, V.N., and W. E. Bentley (1999)
Expression and Purification of Human Interleukin-2 as a Fusion
with Green Fluorescent Protein in Suspended Sf-9 Insect Cells,
Journal of Biotechnology, 69:9-17.
- Cha, H.J., Dalal, N.G., Pham, M.Q., and W.E. Bentley (1999)
Purification of Human Interleukin-2 Fusion Protein Produced in
Insect Larvae is Facilitated by Fusion with Green Fluorescent
Protein and Metal Affinity Ligand, Biotechnology Progress, 15(2),
283-286.
- Wang, M.Y., Wang. S.L., Bentley, W.E., and G.C. Liu (1999)
Using Glucose Feed to Regulate pH Values of Culture Media and
Increase the Production of Baculovirus (BmNPV) and Foreign Protein
(HBsAg), Process Biochemistry, 34:295-301.
- Ramirez, D.L. and W.E. Bentley (1999) Modeling Inducer and
Amino Acid Fed-batch Cultures: Characterization of Cell Stress
and Protein Turnover, Journal of Biotechnology, 71:39-58.
- Hu, Y.-C., Vakharia, V., Edwards, G., and W. E. Bentley (1999)
Chimeric Infectious Bursal Disease Virus-like Particles Expressed
in Insect Cells and Purified by Immobilized Metal Affinity Chromatography,
Biotechnology and Bioengineering, 63:721-729.
- Dalal, N.G., and W. E. Bentley (1999) Mathematical Characterization
of Insect Cell (Sf-9) Death in Suspended Culture, Biotechnology
Letters, 21: 325-329.
- Harcum, S.W., and W. E. Bentley (1999) The Heat-shock and Stringent
Responses have Overlapping Protease Activity in E. coli: Implications
for Heterologous Protein Yield, Applied Biochemistry and Biotechnology,
80:1-15.
- DeLisa, M.P., Li, J.C., Rao, G., Weigand, W.A., and W.E. Bentley
(1999) Monitoring GFP-operon Fusion Protein Expression During
High Cell Density Cultivation of Escherichia coli Using an On-line
Optical Sensor, Biotechnology and Bioengineering, 65:54-64.
- Gill, R.T., Valdes, J.J., and W.E. Bentley (1999) RTPCR Differential
Display Analysis of Escherichia coli Global Gene Regulation in
Response to Heat Shock, Applied and Environmental Microbiology,
65:5386-5393.
- Hu, Y.-C. and W.E. Bentley (1999) Enhancing Yield of Infectious
Bursal Disease Virus Structural Proteins in Baculovirus Expression
Systems: Focus on Media, Protease Inhibitors, and Dissolved Oxygen,
Biotechnology Progress, 15:1065-1071.
- Cha, H.J, Dalal, N.G., Pham, M.Q., Vakharia, V.N., Rao, G.,
and W. E. Bentley (1999) Insect Larval Expression Process is Optimized
by Generating Fusions with Green Fluorescent Protein, Biotechnology
and Bioengineering, 65:316-324.
-
1998
- Gill, R.T., Cha, H.J., Jain, A., Rao, G., and W.E. Bentley
(1998) Generating Controlled Reducing Environments in Aerobic
Recombinant E. coli Fermentations: Effect on Cell Growth, Oxygen
Uptake, and in vivo CAT Activity, Biotechnology and Bioengineering,
59:248-259.
- Albano, R., Randers-Eichhorn, L., Bentley, W.E., and G. Rao
(1998) Green Fluorescent Protein as a Real Time Quantitative Reporter
of Heterologous Protein Production, Biotechnology Progress, 14:
351-354.
- Naggie, S. and W.E. Bentley (1998) Appearance of Protease Activities
Coincides with p10 and polyhedrin-driven Protein Production in
Baculovirus Expression System: Effects on Yield, Biotechnology
Progress, 14:227-232.
- Gotoh, T., Iwanaga, T., Kikuchi, K, and Bentley, WE (1998)
A Novel Support for Membrane Enzyme Immobilization: Gel Beads
Containing Polymerized Phospholipid Vesicles, Biotechnology and
Applied Biochemistry, 27: 197-204.
- Bentley, W.E., Madurawe, R.D., Gill, R.T., Shiloach, M., Chase,
T.E., Pulliam-Holoman, T.R., and J.J. Valdes (1998) Generation
of a Histidine-Tagged Antibotulinum Toxin Antibody Fragment in
E. coli: Effects of Post-induction Temperature on Yield and IMAC
Binding-Affinity, Journal of Industrial Microbiology and Biotechnology,
21:275-282.
-
1997
- Pulliam, T. R., Winston, S., and W.E. Bentley (1997) Tryptophan
Regulated Expression and Aqueous Two-Phase Separation of Recombinant
HIV-Fusion Peptides, Enzyme and Microbial Technology, 20: 47-51.
- Lee, T.-S., Weigand, W.A., and W. E. Bentley (1997) Observations
of Metabolite Formation and Variable Yield in Thiodiglycol Biodegradation
Processes: Impact on Reactor Design, Applied Biochemistry and
Biotechnology, 63/65: 743-757.
- Hu, Y.C., Wang, M.Y., and W.E. Bentley (1997) A Tubular Bioreactor
for the Infection of Insect Cells with Recombinant Baculovirus,
Cytotechnology, 24: 143-152.
- Randers-Eichhorn, L., Albano, C.R., Sipior, J., Bentley, W.E.,
and G. Rao (1997) An On-line Green Fluorescent Protein Sensor
with LED Excitation, Biotechnology and Bioengineering, 55: 921-927.
- Naggie, S., Hu, Y.C., Pulliam-Holoman, T.R., and W.E. Bentley
(1997) Substrate (Gelatin) Gel Electrophoretic Method for Analysis
of Protease Activity in Insect (Sf-9) Cells, Biotechnology Techniques,
11: 297-301.
- Pilon, A., Yost, P., Chase, T. Lohnas, and W.E. Bentley (1997)
Ubiquitin Fusion Technology: Bioprocessing of Peptides, Biotechnology
Progress, 13:374-379.
- Cha, H.J., Pham, M.Q., Rao, G., and W. E. Bentley (1997) Expression
of Green Fluorescent Protein in Insect Larvae and its Application
for Heterologous Protein Production, Biotechnology and Bioengineering,
56:238-243.
- Cha, H.J., Choi, S.S., Yoo, Y.J., and W.E. Bentley (1997) Enhancement
of Production of Cloned Glucoamylase under Low Aeration Condition
from Recombinant Yeast Using a SUC2 Promoter, Process Biochemistry,
32, 679-684.
- Cha, H.J., Gotoh, T., and W. E. Bentley (1997) Simplification
of Titer Determination for Recombinant Baculovirus by Green Fluorescent
Protein Marker, BioTechniques, 23: 782-786.
-
1996
- Pham, M.Q., Harvey, S.P., Weigand, W.A., and W.E. Bentley (1996)
Reactor Comparisons for the Biodegradation of Thiodiglycol, a
Product of Mustard Gas Hydrolysis, Applied Biochemistry and Biotechnology,
57/58: 779-789.
- Wang, M.Y., Pulliam, T.R., Valle, M., Vakharia, V. and W.E.
Bentley (1996) Kinetic Analysis of Alkaline Protease Activity,
Recombinant Protein Production and Metabolites for Infected Insect
(Sf-9) Cells under Different DO Levels, Journal of Biotechnology,
46: 243-254.
- Pilon, A., Yost, P., Chase, T. Lohnas, and W.E. Bentley (1996)
High-level Expression and Efficient Recovery of Ubiquitin Fusion
Proteins from Escherichia coli, Biotechnology Progress, 12:331-337.
- Lee, T.S., Pham, M.Q., Weigand, W.A., Harvey, S.P., and W.E.
Bentley (1996) Bioreactor Strategies for the Treatment of Growth-Inhibitory
Waste: An Analysis of Thiodiglycol Degradation, the Main Hydrolysis
Product of Sulfur Mustard, Biotechnology Progress, 12:533-539.
- Albano, R, Randers-Eichhorn, L., Bentley, W.E., and G. Rao
(1996) Quantitative Measurement of Green Fluorescent Protein Expression
and Chromophore Cyclization, Biotechnology Techniques, 10: 953-958.
-
1995
- Chen, Q., Bentley, W.E. and W. A. Weigand (1995), Optimization
for a Recombinant E. coli Fed-Batch Fermentation, Applied Biochemistry
and Biotechnology, 51/52: 449-461.
- Ko, Y.-F., Bentley, W.E., and W. A. Weigand (1995), The Effect
of Cellular Energetics on Foreign Protein Production, Applied
Biochemistry and Biotechnology, 50:145-159.
- Ramirez, D. M. and W. E. Bentley (1995), Fed-Batch Feeding
and Induction Policies that Improve Foreign Protein Synthesis
and Stability by Avoiding Stress Responses, Biotechnology and
Bioengineering, 47:596-608.
-
1994
- Ko, Y.-F., Bentley, W. E. and W. A. Weigand (1994), A Metabolic
Model of Cellular Energetics and Carbon Flux During Aerobic E.
coli Fermentation, Biotechnology and Bioengineering, 43:847-855
.
- Wang, M.-Y., Bentley, W. E. and V. Vakharia (1994), Purification
of a Recombinant Protein Produced in a Baculovirus Expression
System by Immobilized Metal Affinity Chromatography, Biotechnology
and Bioengineering 43: 349-356.
- Wang, M.-Y. and W. E. Bentley (1994), Continuous Insect Cell
(Sf-9) Culture with Aeration through Sparging, Applied Microbiology
and Biotechnology 41:317-323.
- Bentley, W. E., Wang, M.-Y. and V. Vakharia (1994), Development
of an Efficient Bioprocess for Poultry Vaccines Using High Density
Insect Cell Culture, Annals New York Academy of Sciences 745:336-359.
- Bentley, W.E. (1994), Undergraduate Researchers within a Biochemical
Engineering Research Program: Factors Influencing Research Quality
and Learning Experience, Annual Conference Proceedings, American
Society for Engineering Education, 1994(1):1461-1464.
- Bentley, W.E., Kebede B., Franey, T., and M.Y. Wang (1994),
Segregated Characterization of Recombinant Epoxide Hydrolase Synthesis
via the Baculovirus / Insect Cell Expression System, Chemical
Engineering Science. 49:4133-4141.
- Pulliam, T. R., Winston, S. and W.E. Bentley (1994), Expression
and Aqueous Two-Phase Separation of HIV582-b-gal Fusion Protein,
Journal of Long-Term Effects of Medical Implants. 4(1): 56.
-
1993
- Ramirez, D. M. and W. E. Bentley (1993), Enhancement of Recombinant
Protein Synthesis and Stability via Coordinated Amino Acid Addition,
Biotechnology and Bioengineering, 41:557-565.
- Wang, M.-Y., Kwong, S., and W. E. Bentley (1993), Effects of
Oxygen/Glucose/Glutamine Feeding on Insect Cell Baculovirus Expression:
A Study of Epoxide Hydrolase Production, Biotechnology Progress,
9:355-361.
- Wang, M.-Y., Vakharia, V., and W. E. Bentley (1993), Expression
of Epoxide Hydrolase in Insect Cells: A Focus on the Infected
Cell, Biotechnology and Bioengineering, 42:240-246.
- Bentley, W. E. and O. E. Quiroga (1993), Investigations of
Subpopulation Heterogeneity and Plasmid Stability in Recombinant
E. coli via a Simple Segregated Model, Biotechnology and Bioengineering,
42:222-234.
- Ko, Y.-F., Bentley, W. E. and W. A. Weigand (1993), An Integrated
Metabolic Modeling Approach to Describe the Energy Efficiency
of E. coli Under Oxygen-Limited Conditions: Cellular Energetics
and Carbon Flux, Biotechnology and Bioengineering, 42:843-853.
- Harcum, S. W. and W. E. Bentley (1993), Detection, Quantification,
and Characterization of Proteases in Recombinant Escherichia coli,
Biotechnology Techniques, 7:441-447.
- Harcum, S. W. and W. E. Bentley (1993), Response Dynamics of
26, 34, 39, 54, and 80 kDa Proteases in Induced Cultures of Recombinant
Escherichia coli, Biotechnology and Bioengineering, 42:675-685.
- Wang, M.-Y., Wester, K. and W. E. Bentley (1993), Glutamine
Determination in Insect Cell Culture Media, Biotechnology Techniques,
7:841-846.
-
1992
- Harcum, S. W., Ramirez, D. M. and W. E. Bentley (1992), Optimal
Nutrient Feed Policies for Heterologous Protein Production, Applied
Biochemistry and Biotechnology, 34/35:161-173.
- Bentley, W. E., Davis, R. H. and D. S. Kompala (1991), Dynamics
of Induced CAT Expression in E. coli, Biotechnology and Bioengineering,
38:749-760.
- Bentley, W. E. and D. S. Kompala (1990), Stability in Recombinant
Continuous Cultures - A Metabolic Approach, Biotechnology Letters,
12(5):329-334.
- Bentley, W. E. and D. S. Kompala (1990), Plasmid Instability
in Batch Cultures of Recombinant Bacteria: A Laboratory Experiment,
Chemical Engineering Education, 24(3):168-172.
- Bentley, W. E. and D. S. Kompala (1990), Optimal Induction of
Protein Expression in Recombinant Bacterial Cultures, in Biochemical
Engineering VI, Annals New York Academy of Sciences, 589:120-138.
- Bentley, W.E., Mirjalili, N., Andersen, D. C., Kompala, D. S.
and R. H. Davis (1990), Plasmid Encoded Protein: The Principal Factor
in the "Metabolic Burden" Associated with Recombinant
Bacteria, Biotechnology and Bioengineering, 35(7):668-681.
- Bentley, W. E. and D. S. Kompala (1989), A Novel Structured Kinetic
Modeling Approach for the Analysis of Plasmid Instability in Recombinant
Bacterial Cultures, Biotechnology and Bioengineering, 33(1): 49-61.
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